Cefixima [Spanish]

Cefixima [Spanish] Brand names, Cefixima [Spanish] Analogs

Cefixima [Spanish] Brand Names Mixture

No information avaliable

Cefixima [Spanish] Chemical_Formula

C₁₆H₁₅N₅O₇S₂

Cefixima [Spanish] RX_link

http://www.rxlist.com/cgi/generic/cefixime.htm

Cefixima [Spanish] fda sheet

Cefixima_[Spanish] FDA

Cefixima [Spanish] msds (material safety sheet)

Cefixima_[Spanish] MSDS

Cefixima [Spanish] Synthesis Reference

T. Takaya et al., U.S. Pat. 4,409,214 (1981)

Cefixima [Spanish] Molecular Weight

453.452 g/mol

Cefixima [Spanish] Melting Point

218-225 ^oC

Cefixima [Spanish] H₂O Solubility

55.11 mg/L

Cefixima [Spanish] State

Solid

Cefixima [Spanish] LogP

-0.559

Cefixima [Spanish] Dosage Forms

Oral suspension (100 mg/5 mL); Tablet (200 mg and 400 mg); Powder for solution; Powder for suspension

Cefixima [Spanish] Indication

For use in the treatment of the following infections when caused by susceptible strains of the designated microorganisms: (1) uncomplicated urinary tract infections caused by Escherichia coli and Proteus mirabilis, (2) otitis media caused by Haemophilus influenzae (beta-lactamase positive and negative strains), Moraxella catarrhalis (most of which are beta-lactamase positive), and S. pyogenes, (3) pharyngitis and tonsillitis caused by S. pyogenes, (4) acute bronchitis and acute exacerbations of chronic bronchitis caused by Streptococcus pneumoniae and Haemophilus influenzae (beta-lactamase positive and negative strains), and (5) uncomplicated gonorrhea (cervical/urethral) caused by Neisseria gonorrhoeae (penicillinase- and non-penicillinase-producing strains).

Cefixima [Spanish] Pharmacology

Cefixime, an antibiotic, is a third-generation cephalosporin like ceftriaxone and cefotaxime. Cefixime is highly stable in the presence of beta-lactamase enzymes. As a result, many organisms resistant to penicillins and some cephalosporins due to the presence of beta-lactamases, may be susceptible to cefixime. The antibacterial effect of cefixime results from inhibition of mucopeptide synthesis in the bacterial cell wall.

Cefixima [Spanish] Absorption

About 40%-50% absorbed orally whether administered with or without food, however, time to maximal absorption is increased approximately 0.8 hours when administered with food.

Cefixima [Spanish] side effects and Toxicity

Symptoms of overdose include blood in the urine, diarrhea, nausea, upper abdominal pain, and vomiting.

Cefixima [Spanish] Patient Information

Cefixima [Spanish] Organisms Affected

Enteric bacteria and other eubacteria